1959年科幻片电影《心惊肉跳》讲述A pathologist, Dr. Warren Chapin (played by Vincent Price), discovers that the tingling of the spine in states of extreme fear is due to the growth of a "tingler"—a spinal parasite which can kill the host unless it is destroyed by screaming.由文森特·普莱斯,朱迪思·伊夫林,菲利普·柯立芝,达里尔·希克曼,帕梅拉·林肯等主演。